Which of the following is included in substance use disorder?

Substance use disorder encompasses a broad range of substance misuse, including both legal and illegal substances. This means that it is not limited to just illegal drugs but includes various forms of alcohol and prescription medications as well. The definition takes into account the patterns of use that may lead to significant impairment or distress, regardless of whether the substances are legally permitted or not.

By including the use of alcohol and prescription medications, the choice highlights a comprehensive understanding of substance use issues. Alcohol is widely recognized as a substance that can lead to disorder, and many prescription medications can also be misused or lead to dependency issues. This understanding reflects current diagnostic criteria, which recognize the complexity of substance-related problems occurring across a spectrum of substances.

The other options are too narrow or specific, failing to represent the full scope of what constitutes a substance use disorder.